Why Should I take Probiota Sensitive? The human gastrointestinal tract is home to approximately 100 trillion microorganisms that play a major role in our health. The intestinal microflora is a highly complex community comprised primarily of indigenous species and healthful microorganisms that colonize the bowel when they are consumed on a regular basis. While most intestinal microbes have not been fully characterized, many are believed to be beneficial or commensal in nature, while a small percentage are harmful and can potentially cause disease. This vast and diverse assemblage of microorganisms normally exists in a homeostatic equilibrium that promotes healthy functioning of the gastrointestinal tract and immune system.
When properly balanced, the intestinal microbiota protects against overgrowth of intestinal pathogens, supports normal colonic motility, optimizes digestion, contributes to vitamin and mineral nutriture, facilitates elimination of gut toxins, supports healthy immune responses, and regulates both intestinal and systemic inflammatory processes.
Unfortunately, the delicate microecological balance of the intestinal tract can be disrupted by many factors including poor diet, excessive alcohol intake, use of antibiotics and other medications, stress, aging, and exposure to environmental pollutants. An imbalanced, or dysbiotic, microflora predisposes the host to a variety of infectious, allergic, autoimmune, and inflammatory conditions. Intake of beneficial organisms, known as probiotics, may help support a balanced, protective ecosystem of health-promoting intestinal microbiota.
Key Benefits and Actions.
- Probiotics are living microorganisms that confer health benefits upon the host when taken in adequate amounts. Two generals of bacterial microorganisms have been intensively researched for their probiotic health benefits: Lactobacillus and Bifidobacterium. Lactobacilli are Gram-positive, rod-shaped, facultative anaerobes found throughout the gastrointestinal tract, but predominantly in the small intestine. Bifidobacteria are Gram-positive, microaerophilic or obligate anaerobes that are highly prevalent in the large intestine. Over the past several decades, members of these two bacterial genera have been the subject of numerous studies documenting their beneficial and broad range of health properties.
- Pathogen Antagonism. One of the most important functions of probiotics is to inhibit the growth and activity of harmful intestinal microbes. Probiotics produce a number of substances including lactic acid, acetic acid, formic acid, hydrogen peroxide, and bacteriocins that are toxic to pathogenic organisms. They also compete with pathogens for nutrients and living space, disrupt the formation of pathogenic biofilms, and enhance host defense mechanisms.
- Healthy Gastrointestinal Function. Probiotics optimize gastrointestinal function in a number of ways. Most probiotics produce short-chain fatty acids that nourish colonic mucosal cells, increase colonic blood flow, stimulate mucus production, and facilitate the absorption of water and minerals. Many also secrete enzymes that break down difficult-to-digest dietary carbohydrates like lactose and antigenic proteins like gluten and casein. Probiotics further support intestinal barrier integrity by increasing expression of epithelial tight junction proteins that reduce intestinal permeability.
- Immune Defense. A key benefit of probiotics is their capacity to support both gastrointestinal and systemic immune function. The intestinal tract is the largest immunological organ in the body and the functionality of gut-associated lymphoid tissues (GALT) depends largely on crosstalk between its constituent immune cells and the gut microbiota. A balanced intestinal microflora is crucial to proper development of GALT and enhances the capacity of the immune system to initiate defensive responses. Probiotics have been shown to support leukocyte phagocytosis, augment natural killer (NK) cell cytotoxicity, support healthy immunoglobulin A (IgA) secretion, and promote antibody production.
- Inflammation Modulation. The capacity of probiotics to support healthy inflammatory processes derives from their immunoregulatory activity.* By modulating the function of immune cells, probiotics influence the production of biochemical mediators that govern inflammation.
What makes Probiota Sensitive by Seeking Health Superior to Other Probiotics? Probiota Sensitive contains 12 highly effective Lactobacillus and Bifidobacterium species chosen on the basis of their ability to survive passage through the gastrointestinal tract, antagonize pathogens, improve gastrointestinal function, and support against inflammatory conditions. Probiota Sensitive is a hypoallergenic product, free of all common allergens, colorings, flavorings, preservatives, and salicylates. It is also formulated without inulin and thus suitable for persons who wish to limit or restrict their intake of specific carbohydrates.
Storage : Probiotics are sensitive to warm temperatures and moisture. Keep refrigerated with the lid tightly shut to minimize entry of moisture into the bottle. There is no loss of potency when the package is received as loss of potency with high temperatures only occurs over weeks and not hours or days.